EMDIS message: DONOR_CB

The DONOR_CB message is used to exchange donor and CBU demographic data, and is typically sent in response to patient search requests (i.e. PAT_UPD and PAT_STAT). It should also be sent proactively, whenever relevant donor/CBU data is updated, as described below.

A match run is recommended once a week but has to be performed at least once a month. The repeated transmission of unchanged donors is discouraged. This can be accomplished by running the repeat search program only over new or changed donors (see EMDIS Repeat Search Program). The exact matching behaviour is to be specified separately.

A changed donor (e.g. after DR typing) has to be transmitted to all patients ́s match lists he is on (even if he is different).

Net volume means volume prior to reduction also called pre-processing. The term frozen is used synonymously with post-processing.

The value Q is allowed for the DONOR_CB fields D_CMV, D_TOXO and D_EBV but can be blanked by those hubs which do not allow Q in their donor data set.

The D_STAT_END_DATE is required if the D_STATUS is TU. It’s recommended to provide it if the D_STATUS is RS or OP.

The D_STAT_REASON is required if the D_STATUS is TU or DE.

The new code TQ (typing questionable e.g. after SMP_RES) D_STAT_REASON is only allowed if the D_STATUS is TU.

Although all HLA fields of the DONOR_CB message are defined as optional at a minimum antigen and/or allele values must be provided for the loci A and B.

The default for the donation counts (D_NMBR_MARR and D_NMBR_PBSC) is the empty value i.e. "". Any number and especially 0 (zero) posits explicit information about the number of donations.

If D_COLL_TYPE is empty, it is unknown what the donor is willing to donate.

If the full donor birthdate cannot be provided for privacy reasons, the year of birth has to be given in the form ”YYYY0101”.

D_BIRTH_DATE is a required field for donors (D_TYPE = D).

D_SEX is a required field for donors (D_TYPE = D).

D_CONTACT_DATE and D_CHECKUP_DATE are only allowed for donors (D_TYPE = D).

Some registries maintain a status ’CBU verification typing (CT) complete’ which means the CBU has been confirmatory typed. The requirements for this status differ per registry and are provided in the appropriate national rules. The field CB_CT_COMPLETE_DATE indicates the newest date the CBU got the verification typing (CT) complete status.

CB_CT_COMPLETE_DATE is defined as follows:

Verification typing (CT) (Confirmatory typing) is repeat DNA typing after registration. For the verification tpying (CT) to be complete, loci A, B and DRB1 must all be retested and confirmed consistent with registration typing. The Verification Typing (CT) Complete Date is the latest date that A, B, and DRB1 are all complete. If the loci are not all tested at the same time, this date will be the date the last locus is tested. Date format: YYYYMMDD.

The HLA special code NEW for new alleles is only valid for results containing HLA values (TYP_RES or SMP_RES). The subsequent DONOR_CB message reports the original typing of the donor. For example:

TYP_RES.D_DRB11 = "11:01"
TYP_RES.D_DRB12 = "NEW"
DONOR_CB.D_DRB11 = "old value" (if any)
DONOR_CB.D_DRB12 = "old value" (if any)

D_KIR_GL must be empty. The field was introduced for the future exchange of GL-Strings and/or URI that refers to a GL-string registered with GL-service for KIR typings .